MotoGP Second Free Practice Results Misano San Marino Friday September 17
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. | |||
|---|---|---|---|---|---|---|---|---|
| 1 | Johann Zarco | Pramac Racing | 291.8 | 01:42.097 | | |||
| 2 | Francesco Bagnaia | Ducati Lenovo | 290.3 | 01:42.650 | 0.553 / 0.553 | |||
| 3 | Jack Miller | Ducati Lenovo | 288.7 | 01:42.719 | 0.622 / 0.069 | |||
| 4 | Joan Mir | Suzuki Ecstar | 283.4 | 01:42.910 | 0.813 / 0.191 | |||
| 5 | Marc Marquez | Repsol Honda | 285.7 | 01:42.921 | 0.824 / 0.011 | |||
| 6 | Miguel Oliveira | Red Bull KTM | 282.7 | 01:43.234 | 1.137 / 0.313 | |||
| 7 | Danilo Petrucci | Tech 3 KTM | 285.7 | 01:43.329 | 1.232 / 0.095 | |||
| 8 | Aleix Espargaro | Aprilia Gresini | 286.4 | 01:43.629 | 1.532 / 0.300 | |||
| 9 | Iker Lecuona | Tech 3 KTM | 281.2 | 01:43.722 | 1.625 / 0.093 | |||
| 10 | Alex Marquez | LCR Honda Castrol | 288.0 | 01:43.739 | 1.642 / 0.017 | |||
| 11 | Alex Rins | Suzuki Ecstar | 287.2 | 01:43.760 | 1.663 / 0.021 | |||
| 12 | Michele Pirro* | Ducati Lenovo | 281.9 | 01:43.811 | 1.714 / 0.051 | |||
| 13 | Franco Morbidelli^ | Monster Energy Yamaha | 279.7 | 01:43.844 | 1.747 / 0.033 | |||
| 14 | Enea Bastianini | Esponsorama Racing | 281.9 | 01:43.901 | 1.804 / 0.057 | |||
| 15 | Jorge Martin | Pramac Racing | 289.5 | 01:43.906 | 1.809 / 0.005 | |||
| 16 | Valentino Rossi | Petronas Yamaha | 283.4 | 01:44.130 | 2.033 / 0.224 | |||
| 17 | Maverick Viñales | Aprilia Gresini | 286.4 | 01:44.203 | 2.106 / 0.073 | |||
| 18 | Fabio Quartararo | Monster Energy Yamaha | 282.7 | 01:44.205 | 2.108 / 0.002 | |||
| 19 | Pol Espargaro | Repsol Honda | 287.2 | 01:44.266 | 2.169 / 0.061 | |||
| 20 | Brad Binder | Red Bull KTM | 281.2 | 01:44.404 | 2.307 / 0.138 | |||
| 21 | Andrea Dovizioso° | Petronas Yamaha | 279.0 | 01:44.530 | 2.433 / 0.126 | |||
| 22 | Stefan Bradl* | Honda | 284.2 | 01:44.713 | 2.616 / 0.183 | |||
| 23 | Luca Marini | Sky VR46 Esponsorama | 280.5 | 01:44.970 | 2.873 / 0.257 | |||
| 24 | Takaaki Nakagami | LCR Honda Idemitsu | 281.2 | 01:44.992 | 2.895 / 0.022 |
*Wild card entry (2)
^Replaced former Yamaha rider Maverick Viñales for the rest of the 2021 season
°Replaced Franco Morbidelli for the rest of the 2021 season