MotoGP First Free Practice Results Misano San Marino Friday September 17
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. | |||
|---|---|---|---|---|---|---|---|---|
| 1 | Maverick Viñales | Aprilia Gresini | 295.8 | 01:32.666 | | |||
| 2 | Joan Mir | Suzuki Ecstar | 291.8 | 01:32.746 | 0.080 / 0.080 | |||
| 3 | Francesco Bagnaia | Ducati Lenovo | 294.2 | 01:32.801 | 0.135 / 0.055 | |||
| 4 | Jack Miller | Ducati Lenovo | 296.7 | 01:32.859 | 0.193 / 0.058 | |||
| 5 | Alex Rins | Suzuki Ecstar | 295.0 | 01:32.885 | 0.219 / 0.026 | |||
| 6 | Pol Espargaro | Repsol Honda | 297.5 | 01:33.019 | 0.353 / 0.134 | |||
| 7 | Fabio Quartararo | Monster Energy Yamaha | 288.7 | 01:33.024 | 0.358 / 0.005 | |||
| 8 | Stefan Bradl* | Honda | 295.8 | 01:33.047 | 0.381 / 0.023 | |||
| 9 | Marc Marquez | Repsol Honda | 295.0 | 01:33.100 | 0.434 / 0.053 | |||
| 10 | Aleix Espargaro | Aprilia Gresini | 294.2 | 01:33.102 | 0.436 / 0.002 | |||
| 11 | Johann Zarco | Pramac Racing | 298.3 | 01:33.143 | 0.477 / 0.041 | |||
| 12 | Enea Bastianini | Esponsorama Racing | 296.7 | 01:33.314 | 0.648 / 0.171 | |||
| 13 | Takaaki Nakagami | LCR Honda Idemitsu | 296.7 | 01:33.409 | 0.743 / 0.095 | |||
| 14 | Jorge Martin | Pramac Racing | 295.0 | 01:33.451 | 0.785 / 0.042 | |||
| 15 | Michele Pirro* | Ducati Lenovo | 293.4 | 01:33.482 | 0.816 / 0.031 | |||
| 16 | Franco Morbidelli^ | Monster Energy Yamaha | 286.4 | 01:33.570 | 0.904 / 0.088 | |||
| 17 | Iker Lecuona | Tech 3 KTM | 290.3 | 01:33.710 | 1.044 / 0.140 | |||
| 18 | Alex Marquez | LCR Honda Castrol | 295.8 | 01:33.766 | 1.100 / 0.056 | |||
| 19 | Valentino Rossi | Petronas Yamaha | 289.5 | 01:33.791 | 1.125 / 0.025 | |||
| 20 | Danilo Petrucci | Tech 3 KTM | 288.7 | 01:33.950 | 1.284 / 0.159 | |||
| 21 | Brad Binder | Red Bull KTM | 293.4 | 01:34.022 | 1.356 / 0.072 | |||
| 22 | Miguel Oliveira | Red Bull KTM | 294.2 | 01:34.026 | 1.360 / 0.004 | |||
| 23 | Luca Marini | Sky VR46 Esponsorama | 292.6 | 01:34.037 | 1.371 / 0.011 | |||
| 24 | Andrea Dovizioso° | Petronas Yamaha | 288.0 | 01:35.211 | 2.545 / 1.174 |
*Wild card entry (2)
^Replaced former Yamaha rider Maverick Viñales for the rest of the 2021 season
°Replaced Franco Morbidelli for the rest of the 2021 season