MotoGP Qualifying Results Misano San Marino Saturday September 12
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Marco Bezzecchi | Aprilia Racing | 299.1 | 01:29.982 | |
| 2 | Marc Marquez | Ducati Lenovo | 296.7 | 01:30.180 | 0.198 / 0.198 |
| 3 | Fermin Aldeguer+ | Gresini Racing | 296.7 | 01:30.350 | 0.368 / 0.170 |
| 4 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 297.5 | 01:30.386 | 0.404 / 0.036 |
| 5 | Jorge Martin | Aprilia Racing | 300.0 | 01:30.569 | 0.587 / 0.183 |
| 6 | Luca Marini | Honda HRC Castrol | 299.1 | 01:30.609 | 0.627 / 0.040 |
| 7 | Pedro Acosta | Red Bull KTM | 300.0 | 01:30.640 | 0.658 / 0.031 |
| 8 | Franco Morbidelli | Pertamina Enduro VR46 | 299.1 | 01:30.643 | 0.661 / 0.003 |
| 9 | Alex Marquez | Gresini Racing | 299.1 | 01:30.696 | 0.714 / 0.053 |
| 10 | Raul Fernandez+ | Trackhouse Racing | 295.0 | 01:30.853 | 0.871 / 0.157 |
| 11 | Johann Zarco | Castrol Honda LCR | 300.0 | 01:30.887 | 0.905 / 0.034 |
| 12 | Pol Espargaro* | KTM Tech3 | 300.0 | 01:31.180 | 1.198 / 0.293 |
+Riders advanced from Q1 to Q2
| 13 | Fabio Quartararo | Monster Energy Yamaha | 294.2 | 01:30.799 | 0.264 / 0.222 |
| 14 | Francesco Bagnaia | Ducati Lenovo | 299.1 | 01:30.916 | 0.381 / 0.117 |
| 15 | Diogo Moreira | Pro Honda LCR | 299.1 | 01:30.966 | 0.431 / 0.050 |
| 16 | Enea Bastianini | KTM Tech3 | 296.7 | 01:31.113 | 0.578 / 0.147 |
| 17 | Joan Mir | Honda HRC Castrol | 300.0 | 01:31.149 | 0.614 / 0.036 |
| 18 | Jack Miller | Pramac Racing | 295.8 | 01:31.413 | 0.878 / 0.264 |
| 19 | Brad Binder | Red Bull KTM | 298.3 | 01:31.552 | 1.017 / 0.139 |
| 20 | Alex Rins | Monster Energy Yamaha | 295.0 | 01:31.593 | 1.058 / 0.041 |
| 21 | Toprak Razgatlıoğlu | Pramac Racing | 292.6 | 01:32.264 | 1.729 / 0.671 |
*Replaces Maverick Viñales for the San Marino Grand Prix
Note: Red Bull KTM Tech3 rider Maverick Viñales (left shoulder injury recovery) and SuperFile Trackhouse's Ai Ogura (left hand injury recovery) were ruled out of the San Marino Grand Prix.