Formula 1 Second Free Practice Results Madrid Spain Friday September 11
| P | Driver | Team | Lap time | Laps |
| 1 | Andrea Antonelli | Mercedes | 01:33.662 | 24 |
| 2 | Charles Leclerc | Scuderia Ferrari | 01:33.775 | 26 |
| 3 | Lewis Hamilton | Scuderia Ferrari | 01:33.811 | 23 |
| 4 | Arvid Lindblad | Racing Bulls | 01:33.890 | 15 |
| 5 | George Russell | Mercedes | 01:33.999 | 25 |
| 6 | Max Verstappen | Red Bull Racing | 01:34.063 | 22 |
| 7 | Oscar Piastri | McLaren | 01:34.200 | 24 |
| 8 | Yuki Tsunoda^ | Racing Bulls | 01:34.758 | 26 |
| 9 | Esteban Ocon | Haas | 01:34.867 | 26 |
| 10 | Liam Lawson* | Red Bull Racing | 01:34.938 | 21 |
| 11 | Pierre Gasly | Alpine | 01:34.959 | 21 |
| 12 | Nico Hülkenberg | Audi | 01:35.060 | 22 |
| 13 | Gabriel Bortoleto | Audi | 01:35.170 | 25 |
| 14 | Oliver Bearman | Haas | 01:35.203 | 26 |
| 15 | Franco Colapinto | Alpine | 01:35.886 | 22 |
| 16 | Carlos Sainz | Williams | 01:36.291 | 25 |
| 17 | Fernando Alonso | Aston Martin | 01:36.780 | 16 |
| 18 | Alexander Albon | Williams | 01:36.936 | 22 |
| 19 | Sergio Perez | Cadillac | 01:37.195 | 24 |
| 20 | Lance Stroll | Aston Martin | 01:37.273 | 20 |
| 21 | Valtteri Bottas | Cadillac | 01:37.727 | 24 |
| 22 | Lando Norris | McLaren | no time | 2 |
*Replaces Isack Hadjar at Red Bull Racing for the Spanish Grand Prix
^Replaces Liam Lawson at Racing Bulls for the Spanish Grand Prix
Note: Oracle Red Bull Racing driver Isack Hadjar (wrist injury recovery) was ruled out of the Spanish Grand Prix.