MotoGP Second Free Practice Results Mandalika Indonesia Saturday October 10
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Marco Bezzecchi | Aprilia Racing | 317.6 | 01:29.560 | |
| 2 | Raul Fernandez | Trackhouse Racing | 312.1 | 01:29.734 | 0.174 / 0.174 |
| 3 | Marc Marquez | Ducati Lenovo | 317.6 | 01:29.871 | 0.311 / 0.137 |
| 4 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 315.7 | 01:29.919 | 0.359 / 0.048 |
| 5 | Jorge Martin | Aprilia Racing | 317.6 | 01:29.948 | 0.388 / 0.029 |
| 6 | Pedro Acosta | Red Bull KTM | 318.5 | 01:30.064 | 0.504 / 0.116 |
| 7 | Ai Ogura | Trackhouse Racing | 315.7 | 01:30.143 | 0.583 / 0.079 |
| 8 | Fermin Aldeguer | Gresini Racing | 313.9 | 01:30.311 | 0.751 / 0.168 |
| 9 | Francesco Bagnaia | Ducati Lenovo | 320.4 | 01:30.414 | 0.854 / 0.103 |
| 10 | Alex Marquez | Gresini Racing | 317.6 | 01:30.428 | 0.868 / 0.014 |
| 11 | Alex Rins | Monster Energy Yamaha | 312.1 | 01:30.439 | 0.879 / 0.011 |
| 12 | Enea Bastianini | KTM Tech3 | 317.6 | 01:30.498 | 0.938 / 0.059 |
| 13 | Fabio Quartararo | Monster Energy Yamaha | 314.8 | 01:30.508 | 0.948 / 0.010 |
| 14 | Franco Morbidelli | Pertamina Enduro VR46 | 314.8 | 01:30.682 | 1.122 / 0.174 |
| 15 | Johann Zarco | Castrol Honda LCR | 315.7 | 01:30.691 | 1.131 / 0.009 |
| 16 | Diogo Moreira | Pro Honda LCR | 318.5 | 01:30.693 | 1.133 / 0.002 |
| 17 | Luca Marini | Honda HRC Castrol | 316.7 | 01:30.759 | 1.199 / 0.066 |
| 18 | Brad Binder | Red Bull KTM | 316.7 | 01:30.953 | 1.393 / 0.194 |
| 19 | Toprak Razgatlıoğlu | Pramac Racing | 312.1 | 01:31.133 | 1.573 / 0.180 |
| 20 | Maverick Viñales | KTM Tech3 | 315.7 | 01:31.168 | 1.608 / 0.035 |
| 21 | Jack Miller | Pramac Racing | 309.4 | 01:31.366 | 1.806 / 0.198 |
| 22 | Aleix Espargaro* | Honda HRC Castrol | 313.9 | 01:31.380 | 1.820 / 0.014 |
*Replaces Joan Mir for the Indonesian Grand Prix
Note: Honda HRC Castrol rider Joan Mir (physical health recovery) was ruled out of the Indonesian Grand Prix.