MotoGP Second Free Practice Results Sepang Malaysia Saturday October 31
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Enea Bastianini | KTM Tech3 | 337.5 | 01:58.516 | |
| 2 | Alex Marquez | Gresini Racing | 339.6 | 01:58.804 | 0.288 / 0.288 |
| 3 | Marco Bezzecchi | Aprilia Racing | 336.4 | 01:58.929 | 0.413 / 0.125 |
| 4 | Ai Ogura | Trackhouse Racing | 333.3 | 01:58.973 | 0.457 / 0.044 |
| 5 | Pedro Acosta | Red Bull KTM | 339.6 | 01:59.009 | 0.493 / 0.036 |
| 6 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 334.3 | 01:59.035 | 0.519 / 0.026 |
| 7 | Luca Marini | Honda HRC Castrol | 336.4 | 01:59.067 | 0.551 / 0.032 |
| 8 | Marc Marquez | Ducati Lenovo | 338.5 | 01:59.097 | 0.581 / 0.030 |
| 9 | Franco Morbidelli | Pertamina Enduro VR46 | 335.4 | 01:59.140 | 0.624 / 0.043 |
| 10 | Francesco Bagnaia | Ducati Lenovo | 340.6 | 01:59.153 | 0.637 / 0.013 |
| 11 | Johann Zarco | Castrol Honda LCR | 335.4 | 01:59.201 | 0.685 / 0.048 |
| 12 | Maverick Viñales | KTM Tech3 | 334.3 | 01:59.271 | 0.755 / 0.070 |
| 13 | Diogo Moreira | Pro Honda LCR | 335.4 | 01:59.321 | 0.805 / 0.050 |
| 14 | Joan Mir | Honda HRC Castrol | 338.5 | 01:59.543 | 1.027 / 0.222 |
| 15 | Iker Lecuona^ | Gresini Racing | 331.2 | 01:59.685 | 1.169 / 0.142 |
| 16 | Brad Binder | Red Bull KTM | 338.5 | 01:59.750 | 1.234 / 0.065 |
| 17 | Fabio Quartararo | Monster Energy Yamaha | 333.3 | 01:59.775 | 1.259 / 0.025 |
| 18 | Alex Rins | Monster Energy Yamaha | 333.3 | 01:59.930 | 1.414 / 0.155 |
| 19 | Jack Miller | Pramac Racing | 332.3 | 02:00.023 | 1.507 / 0.093 |
| 20 | Augusto Fernandez* | Pramac Racing | 327.2 | 02:00.159 | 1.643 / 0.136 |
| 21 | Jorge Martin | Aprilia Racing | 333.3 | 02:00.359 | 1.843 / 0.200 |
*Replaces Toprak Razgatlıoğlu for the Malaysian Grand Prix
^Replaces Fermin Aldeguer for the Malaysian Grand Prix
Note: Trackhouse rider Raul Fernandez (finger injury) was declared unfit for the Malaysian Grand Prix following a brief stint in FP1.
Pramac Racing rider Toprak Razgatlıoğlu (right shoulder injury recovery) and Gresini Racing's Fermin Aldeguer (right hand injury recovery) were ruled out of the Malaysian Grand Prix.