MotoGP Second Free Practice Results Goiânia Brazil Saturday March 21
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Ai Ogura | Trackhouse Racing | 340.6 | 01:18.237 | |
| 2 | Marc Marquez | Ducati Lenovo | 346.1 | 01:18.248 | 0.011 / 0.011 |
| 3 | Jorge Martin | Aprilia Racing | 340.6 | 01:18.405 | 0.168 / 0.157 |
| 4 | Francesco Bagnaia | Ducati Lenovo | 343.9 | 01:18.518 | 0.281 / 0.113 |
| 5 | Pedro Acosta | Red Bull KTM | 342.8 | 01:18.616 | 0.379 / 0.098 |
| 6 | Joan Mir | Honda HRC Castrol | 341.7 | 01:18.771 | 0.534 / 0.155 |
| 7 | Maverick Viñales | KTM Tech3 | 338.5 | 01:18.792 | 0.555 / 0.021 |
| 8 | Franco Morbidelli | Pertamina Enduro VR46 | 338.5 | 01:18.834 | 0.597 / 0.042 |
| 9 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 341.7 | 01:18.852 | 0.615 / 0.018 |
| 10 | Marco Bezzecchi | Aprilia Racing | 342.8 | 01:18.864 | 0.627 / 0.012 |
| 11 | Alex Rins | Monster Energy Yamaha | 338.5 | 01:18.921 | 0.684 / 0.057 |
| 12 | Fabio Quartararo | Monster Energy Yamaha | 337.5 | 01:18.929 | 0.692 / 0.008 |
| 13 | Toprak Razgatlıoğlu | Pramac Racing | 337.5 | 01:18.950 | 0.713 / 0.021 |
| 14 | Diogo Moreira | Pro Honda LCR | 341.7 | 01:19.075 | 0.838 / 0.125 |
| 15 | Alex Marquez | Gresini Racing | 346.1 | 01:19.076 | 0.839 / 0.001 |
| 16 | Enea Bastianini | KTM Tech3 | 341.7 | 01:19.109 | 0.872 / 0.033 |
| 17 | Luca Marini | Honda HRC Castrol | 341.7 | 01:19.129 | 0.892 / 0.020 |
| 18 | Raul Fernandez | Trackhouse Racing | 336.4 | 01:19.139 | 0.902 / 0.010 |
| 19 | Jack Miller | Pramac Racing | 338.5 | 01:19.212 | 0.975 / 0.073 |
| 20 | Johann Zarco | Castrol Honda LCR | 339.6 | 01:19.233 | 0.996 / 0.021 |
| 21 | Brad Binder | Red Bull KTM | 341.7 | 01:19.381 | 1.144 / 0.148 |
| 22 | Fermin Aldeguer | Gresini Racing | 342.8 | 01:19.493 | 1.256 / 0.112 |