MotoGP Practice Results Austin United States Friday March 27
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Marc Marquez | Ducati Lenovo | 341.3 | 02:00.927 | |
| 2 | Ai Ogura | Trackhouse Racing | 343.5 | 02:00.980 | 0.053 / 0.053 |
| 3 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 336.9 | 02:01.114 | 0.187 / 0.134 |
| 4 | Marco Bezzecchi | Aprilia Racing | 344.7 | 02:01.127 | 0.200 / 0.013 |
| 5 | Alex Marquez | Gresini Racing | 340.2 | 02:01.213 | 0.286 / 0.086 |
| 6 | Pedro Acosta | Red Bull KTM | 343.5 | 02:01.250 | 0.323 / 0.037 |
| 7 | Jorge Martin | Aprilia Racing | 343.5 | 02:01.265 | 0.338 / 0.015 |
| 8 | Francesco Bagnaia | Ducati Lenovo | 344.7 | 02:01.371 | 0.444 / 0.106 |
| 9 | Luca Marini | Honda HRC Castrol | 342.4 | 02:01.494 | 0.567 / 0.123 |
| 10 | Enea Bastianini | KTM Tech3 | 342.4 | 02:01.579 | 0.652 / 0.085 |
| 11 | Joan Mir | Honda HRC Castrol | 345.8 | 02:01.611 | 0.684 / 0.032 |
| 12 | Fermin Aldeguer | Gresini Racing | 333.7 | 02:01.656 | 0.729 / 0.045 |
| 13 | Raul Fernandez | Trackhouse Racing | 339.1 | 02:01.781 | 0.854 / 0.125 |
| 14 | Johann Zarco | Castrol Honda LCR | 341.3 | 02:01.952 | 1.025 / 0.171 |
| 15 | Fabio Quartararo | Monster Energy Yamaha | 341.3 | 02:02.037 | 1.110 / 0.085 |
| 16 | Jack Miller | Pramac Racing | 334.8 | 02:02.242 | 1.315 / 0.205 |
| 17 | Diogo Moreira | Pro Honda LCR | 339.1 | 02:02.307 | 1.380 / 0.065 |
| 18 | Toprak Razgatlıoğlu | Pramac Racing | 339.1 | 02:02.373 | 1.446 / 0.066 |
| 19 | Brad Binder | Red Bull KTM | 343.5 | 02:02.437 | 1.510 / 0.064 |
| 20 | Franco Morbidelli | Pertamina Enduro VR46 | 339.1 | 02:02.556 | 1.629 / 0.119 |
| 21 | Alex Rins | Monster Energy Yamaha | 343.5 | 02:03.038 | 2.111 / 0.482 |
Note: Red Bull KTM Tech3 rider Maverick Viñales withdrew from the United States Grand Prix following FP1 due to discomfort in his left shoulder.