| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. | |||
|---|---|---|---|---|---|---|---|---|
| 1 | Fabio Quartararo | Petronas Yamaha | 285.7 | 01:37.710 | ||||
| 2 | Andrea Dovizioso | Ducati | 291.8 | 01:37.824 | 0.114 / 0.114 | |||
| 3 | Maverick Viñales | Monster Energy Yamaha | 286.4 | 01:37.848 | 0.138 / 0.024 | |||
| 4 | Francesco Bagnaia | Pramac Racing | 292.6 | 01:37.862 | 0.152 / 0.014 | |||
| 5 | Takaaki Nakagami | LCR Honda Idemitsu | 288.0 | 01:37.902 | 0.192 / 0.040 | |||
| 6 | Brad Binder | Red Bull KTM | 288.0 | 01:38.002 | 0.292 / 0.100 | |||
| 7 | Aleix Espargaro | Aprilia Gresini | 288.0 | 01:38.018 | 0.308 / 0.016 | |||
| 8 | Joan Mir | Suzuki Ecstar | 287.2 | 01:38.025 | 0.315 / 0.007 | |||
| 9 | Franco Morbidelli | Petronas Yamaha | 284.9 | 01:38.039 | 0.329 / 0.014 | |||
| 10 | Pol Espargaro | Red Bull KTM | 289.5 | 01:38.072 | 0.362 / 0.033 | |||
| 11 | Danilo Petrucci | Ducati | 291.8 | 01:38.139 | 0.429 / 0.067 | |||
| 12 | Valentino Rossi | Monster Energy Yamaha | 287.2 | 01:38.188 | 0.478 / 0.049 | |||
| 13 | Miguel Oliveira | KTM Tech 3 | 286.4 | 01:38.198 | 0.488 / 0.010 | |||
| 14 | Jack Miller | Pramac Racing | 291.8 | 01:38.256 | 0.546 / 0.058 | |||
| 15 | Johann Zarco | Hublot Reale Avintia | 288.7 | 01:38.342 | 0.632 / 0.086 | |||
| 16 | Alex Marquez | Repsol Honda | 288.0 | 01:38.701 | 0.991 / 0.359 | |||
| 17 | Cal Crutchlow | LCR Honda Castrol | 287.2 | 01:38.715 | 1.005 / 0.014 | |||
| 18 | Iker Lecuona | KTM Tech 3 | 287.2 | 01:38.824 | 1.114 / 0.109 | |||
| 19 | Bradley Smith | Aprilia Gresini | 286.4 | 01:38.958 | 1.248 / 0.134 | |||
| 20 | Tito Rabat | Hublot Reale Avintia | 286.4 | 01:39.305 | 1.595 / 0.347 | |||
| 21 | Alex Rins | Suzuki Ecstar | 282.7 | 01:43.557 | 5.847 / 4.252 |
Note: Repsol Honda rider Marc Marquez withdrew from the Andalusian Grand Prix after completing an outlap in Q1