MotoGP Second Free Practice Results Misano Italy Friday September 18
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. | |||
|---|---|---|---|---|---|---|---|---|
| 1 | Brad Binder | Red Bull KTM | 294.2 | 01:31.628 | | |||
| 2 | Takaaki Nakagami | LCR Honda Idemitsu | 295.0 | 01:31.630 | 0.002 / 0.002 | |||
| 3 | Fabio Quartararo | Petronas Yamaha | 288.7 | 01:31.644 | 0.016 / 0.014 | |||
| 4 | Maverick Viñales | Monster Energy Yamaha | 291.1 | 01:31.669 | 0.041 / 0.025 | |||
| 5 | Pol Espargaro | Red Bull KTM | 298.3 | 01:31.699 | 0.071 / 0.030 | |||
| 6 | Danilo Petrucci | Ducati | 295.8 | 01:31.973 | 0.345 / 0.274 | |||
| 7 | Miguel Oliveira | KTM Tech 3 | 295.8 | 01:32.032 | 0.404 / 0.059 | |||
| 8 | Johann Zarco | Esponsorama Racing | 294.2 | 01:32.072 | 0.444 / 0.040 | |||
| 9 | Joan Mir | Suzuki Ecstar | 291.8 | 01:32.126 | 0.498 / 0.054 | |||
| 10 | Francesco Bagnaia | Pramac Racing | 297.5 | 01:32.138 | 0.510 / 0.012 | |||
| 11 | Iker Lecuona | KTM Tech 3 | 289.5 | 01:32.238 | 0.610 / 0.100 | |||
| 12 | Valentino Rossi | Monster Energy Yamaha | 288.7 | 01:32.263 | 0.635 / 0.025 | |||
| 13 | Jack Miller | Pramac Racing | 297.5 | 01:32.279 | 0.651 / 0.016 | |||
| 14 | Franco Morbidelli | Petronas Yamaha | 288.0 | 01:32.307 | 0.679 / 0.028 | |||
| 15 | Aleix Espargaro | Aprilia Gresini | 291.8 | 01:32.339 | 0.711 / 0.032 | |||
| 16 | Alex Marquez | Repsol Honda | 296.7 | 01:32.369 | 0.741 / 0.030 | |||
| 17 | Alex Rins | Suzuki Ecstar | 293.4 | 01:32.407 | 0.779 / 0.038 | |||
| 18 | Andrea Dovizioso | Ducati | 295.0 | 01:32.692 | 1.064 / 0.285 | |||
| 19 | Tito Rabat | Esponsorama Racing | 293.4 | 01:32.788 | 1.160 / 0.096 | |||
| 20 | Bradley Smith | Aprilia Gresini | 292.6 | 01:32.916 | 1.288 / 0.128 |
Note: Repsol Honda rider Stefan Bradl withdrew from the remainder of the Emilia Romagna Grand Prix due to an arm injury
LCR Honda Castrol rider Cal Crutchlow was declared unfit for the Emilia Romagna Grand Prix following his arm pump surgery