Formula 1 Second Free Practice Results Austin United States Friday October 22
| P | Driver | Team | Lap time | Laps |
| 1 | Sergio Perez | Red Bull Racing | 01:34.946 | 24 |
| 2 | Lando Norris | McLaren | 01:35.203 | 20 |
| 3 | Lewis Hamilton | Mercedes |
01:35.310 | 22 |
| 4 | Valtteri Bottas | Mercedes |
01:35.360 | 24 |
| 5 | Daniel Ricciardo | McLaren | 01:35.457 | 21 |
| 6 | Lance Stroll | Aston Martin | 01:35.561 | 25 |
| 7 | Charles Leclerc | Scuderia Ferrari | 01:35.572 | 23 |
| 8 | Max Verstappen | Red Bull Racing | 01:35.824 | 23 |
| 9 | Carlos Sainz | Scuderia Ferrari | 01:35.919 | 24 |
| 10 | Antonio Giovinazzi | Alfa Romeo | 01:36.138 | 26 |
| 11 | Esteban Ocon | Alpine | 01:36.158 | 23 |
| 12 | Pierre Gasly | AlphaTauri | 01:36.242 | 25 |
| 13 | Fernando Alonso | Alpine | 01:36.376 | 18 |
| 14 | Kimi Räikkönen | Alfa Romeo | 01:36.558 | 25 |
| 15 | Sebastian Vettel | Aston Martin | 01:36.718 | 30 |
| 16 | Yuki Tsunoda | AlphaTauri | 01:36.983 | 24 |
| 17 | Mick Schumacher | Haas | 01:37.041 | 24 |
| 18 | Nicholas Latifi | Williams | 01:37.254 | 26 |
| 19 | George Russell | Williams | 01:37.490 | 21 |
| 20 | Nikita Mazepin | Haas | 01:38.026 | 23 |