MotoGP Second Free Practice Results Misano San Marino Friday September 2
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Enea Bastianini | Gresini Racing | 299.1 | 01:31.517 | |
| 2 | Francesco Bagnaia | Ducati Lenovo | 299.1 | 01:31.631 | 0.114 / 0.114 |
| 3 | Jack Miller | Ducati Lenovo | 296.7 | 01:31.702 | 0.185 / 0.071 |
| 4 | Johann Zarco | Pramac Racing | 295.8 | 01:31.837 | 0.320 / 0.135 |
| 5 | Fabio Quartararo | Monster Energy Yamaha | 293.4 | 01:31.843 | 0.326 / 0.006 |
| 6 | Maverick Viñales | Aprilia Racing | 298.3 | 01:31.882 | 0.365 / 0.039 |
| 7 | Aleix Espargaro | Aprilia Racing | 297.5 | 01:31.929 | 0.412 / 0.047 |
| 8 | Jorge Martin | Pramac Racing | 296.7 | 01:32.166 | 0.649 / 0.237 |
| 9 | Marco Bezzecchi | Mooney VR46 Racing | 297.5 | 01:32.191 | 0.674 / 0.025 |
| 10 | Franco Morbidelli | Monster Energy Yamaha | 292.6 | 01:32.242 | 0.725 / 0.051 |
| 11 | Pol Espargaro | Repsol Honda | 294.2 | 01:32.301 | 0.784 / 0.059 |
| 12 | Miguel Oliveira | Red Bull KTM | 295.0 | 01:32.330 | 0.813 / 0.029 |
| 13 | Brad Binder | Red Bull KTM | 295.8 | 01:32.358 | 0.841 / 0.028 |
| 14 | Alex Rins | Suzuki Ecstar | 295.0 | 01:32.365 | 0.848 / 0.007 |
| 15 | Alex Marquez | LCR Honda Castrol | 294.2 | 01:32.418 | 0.901 / 0.053 |
| 16 | Takaaki Nakagami | LCR Honda Idemitsu | 291.8 | 01:32.566 | 1.049 / 0.148 |
| 17 | Fabio Di Giannantonio | Gresini Racing | 296.7 | 01:32.656 | 1.139 / 0.090 |
| 18 | Michele Pirro* | Aruba.it Racing | 294.2 | 01:32.673 | 1.156 / 0.017 |
| 19 | Luca Marini | Mooney VR46 Racing | 298.3 | 01:32.749 | 1.232 / 0.076 |
| 20 | Andrea Dovizioso | WithU Yamaha RNF | 291.8 | 01:32.894 | 1.377 / 0.145 |
| 21 | Stefan Bradl^ | Repsol Honda | 291.8 | 01:32.978 | 1.461 / 0.084 |
| 22 | Raul Fernandez | Tech 3 KTM | 292.6 | 01:33.200 | 1.683 / 0.222 |
| 23 | Remy Gardner | Tech 3 KTM | 289.5 | 01:33.559 | 2.042 / 0.359 |
| 24 | Darryn Binder | WithU Yamaha RNF | 294.2 | 01:33.608 | 2.091 / 0.049 |
| 25 | Kazuki Watanabe° | Suzuki Ecstar | 290.3 | 01:36.019 | 4.502 / 2.411 |
*Wild card entry
^Replaced Marc Marquez for the San Marino Grand Prix
°Replaced Joan Mir for the San Marino Grand Prix