Formula 1 Second Free Practice Results São Paulo Brazil Saturday November 12
| P | Driver | Team | Lap time | Laps |
| 1 | Esteban Ocon | Alpine | 01:14.604 | 28 |
| 2 | Sergio Perez | Red Bull Racing | 01:14.788 | 36 |
| 3 | George Russell | Mercedes | 01:14.916 | 31 |
| 4 | Fernando Alonso | Alpine | 01:15.049 | 29 |
| 5 | Max Verstappen | Red Bull Racing | 01:15.098 | 30 |
| 6 | Lewis Hamilton | Mercedes | 01:15.137 | 33 |
| 7 | Pierre Gasly | AlphaTauri | 01:15.636 | 32 |
| 8 | Mick Schumacher | Haas | 01:15.684 | 40 |
| 9 | Kevin Magnussen | Haas | 01:15.815 | 38 |
| 10 | Lando Norris | McLaren | 01:15.851 | 25 |
| 11 | Carlos Sainz | Scuderia Ferrari | 01:15.856 | 38 |
| 12 | Yuki Tsunoda | AlphaTauri | 01:15.865 | 32 |
| 13 | Charles Leclerc | Scuderia Ferrari | 01:15.868 | 37 |
| 14 | Daniel Ricciardo | McLaren | 01:15.994 | 28 |
| 15 | Valtteri Bottas | Alfa Romeo | 01:16.047 | 34 |
| 16 | Nicholas Latifi | Williams | 01:16.181 | 34 |
| 17 | Lance Stroll | Aston Martin | 01:16.263 | 43 |
| 18 | Sebastian Vettel | Aston Martin | 01:16.400 | 44 |
| 19 | Guanyu Zhou | Alfa Romeo | 01:16.468 | 37 |
| 20 | Logan Sargeant* | Williams | 01:16.480 | 28 |
*Substitute for Alexander Albon