MotoGP First Practice Results Le Mans France Friday May 12
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Jack Miller | Red Bull KTM | 313.5 | 01:31.449 | |
| 2 | Luca Marini | Mooney VR46 Racing | 314.5 | 01:31.544 | 0.095 / 0.095 |
| 3 | Brad Binder | Red Bull KTM | 312.6 | 01:31.667 | 0.218 / 0.123 |
| 4 | Johann Zarco | Pramac Racing | 313.5 | 01:31.764 | 0.315 / 0.097 |
| 5 | Alex Marquez | Gresini Racing | 312.6 | 01:31.787 | 0.338 / 0.023 |
| 6 | Joan Mir | Repsol Honda | 307.7 | 01:31.800 | 0.351 / 0.013 |
| 7 | Aleix Espargaro | Aprilia Racing | 312.6 | 01:31.802 | 0.353 / 0.002 |
| 8 | Marco Bezzecchi | Mooney VR46 Racing | 313.5 | 01:31.872 | 0.423 / 0.070 |
| 9 | Maverick Viñales | Aprilia Racing | 314.5 | 01:31.890 | 0.441 / 0.018 |
| 10 | Francesco Bagnaia | Ducati Lenovo | 317.5 | 01:31.915 | 0.466 / 0.025 |
| 11 | Fabio Quartararo | Monster Energy Yamaha | 312.6 | 01:31.946 | 0.497 / 0.031 |
| 12 | Marc Marquez | Repsol Honda | 308.7 | 01:31.973 | 0.524 / 0.027 |
| 13 | Franco Morbidelli | Monster Energy Yamaha | 309.6 | 01:32.153 | 0.704 / 0.180 |
| 14 | Augusto Fernandez | GASGAS Tech3 | 309.6 | 01:32.174 | 0.725 / 0.021 |
| 15 | Takaaki Nakagami | LCR Honda Idemitsu | 313.5 | 01:32.265 | 0.816 / 0.091 |
| 16 | Jorge Martin | Pramac Racing | 317.5 | 01:32.296 | 0.847 / 0.031 |
| 17 | Fabio Di Giannantonio | Gresini Racing | 311.6 | 01:32.710 | 1.261 / 0.414 |
| 18 | Alex Rins | LCR Honda Castrol | 312.6 | 01:32.909 | 1.460 / 0.199 |
| 19 | Danilo Petrucci* | Ducati Lenovo | 313.5 | 01:33.168 | 1.719 / 0.259 |
| 20 | Lorenzo Savadori^ | RNF MotoGP | 306.8 | 01:33.973 | 2.524 / 0.805 |
| 21 | Jonas Folger° | GASGAS Tech3 | 312.6 | 01:34.766 | 3.317 / 0.793 |
| 22 | Raul Fernandez | RNF MotoGP | 287.3 | 01.43.072 | 11.623 / 8.306 |
*Replaced Enea Bastianini for the French Grand Prix
^Replaced Miguel Oliveira for the French Grand Prix
°Replaced Pol Espargaro for the French Grand Prix