MotoGP Second Practice Results Hohenstein-Ernstthal Germany Friday June 16
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Marco Bezzecchi | Mooney VR46 Racing | 301.6 | 01:20.271 | |
| 2 | Jorge Martin | Pramac Racing | 300.8 | 01:20.311 | 0.040 / 0.040 |
| 3 | Aleix Espargaro | Aprilia Racing | 300.0 | 01:20.352 | 0.081 / 0.041 |
| 4 | Francesco Bagnaia | Ducati Lenovo | 301.6 | 01:20.371 | 0.100 / 0.019 |
| 5 | Jack Miller | Red Bull KTM | 300.0 | 01:20.420 | 0.149 / 0.049 |
| 6 | Fabio Quartararo | Monster Energy Yamaha | 297.5 | 01:20.623 | 0.352 / 0.203 |
| 7 | Luca Marini | Mooney VR46 Racing | 301.6 | 01:20.639 | 0.368 / 0.016 |
| 8 | Enea Bastianini | Ducati Lenovo | 300.8 | 01:20.657 | 0.386 / 0.018 |
| 9 | Alex Marquez | Gresini Racing | 299.1 | 01:20.671 | 0.400 / 0.014 |
| 10 | Brad Binder | Red Bull KTM | 302.5 | 01:20.765 | 0.494 / 0.094 |
| 11 | Fabio Di Giannantonio | Gresini Racing | 296.7 | 01:20.799 | 0.528 / 0.034 |
| 12 | Augusto Fernandez | GASGAS Tech3 | 299.1 | 01:20.818 | 0.547 / 0.019 |
| 13 | Miguel Oliveira | RNF MotoGP | 298.3 | 01:20.862 | 0.591 / 0.044 |
| 14 | Johann Zarco | Pramac Racing | 298.3 | 01:20.875 | 0.604 / 0.013 |
| 15 | Maverick Viñales | Aprilia Racing | 300.8 | 01:20.885 | 0.614 / 0.010 |
| 16 | Franco Morbidelli | Monster Energy Yamaha | 299.1 | 01:21.122 | 0.851 / 0.237 |
| 17 | Raul Fernandez | RNF MotoGP | 295.8 | 01:21.857 | 1.586 / 0.735 |
| 18 | Marc Marquez | Repsol Honda | 296.7 | 01:22.141 | 1.870 / 0.284 |
| 19 | Jonas Folger* | GASGAS Tech3 | 294.2 | 01:22.905 | 2.634 / 0.764 |
| 20 | Takaaki Nakagami | LCR Honda Idemitsu | 289.5 | 01:23.950 | 3.679 / 1.045 |
*Replaced Pol Espargaro for the German Grand Prix
Note: Repsol Honda rider Joan Mir and LCR Honda Castrol's Alex Rins were ruled out for the German Grand Prix due to injuries.