MotoGP Practice Results Motegi Japan Friday September 29
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Brad Binder | Red Bull KTM | 315.7 | 01:43.489 | |
| 2 | Francesco Bagnaia | Ducati Lenovo | 314.8 | 01:43.518 | 0.029 / 0.029 |
| 3 | Aleix Espargaro | Aprilia Racing | 309.4 | 01:43.784 | 0.295 / 0.266 |
| 4 | Jorge Martin | Pramac Racing | 313.0 | 01:43.843 | 0.354 / 0.059 |
| 5 | Marco Bezzecchi | Mooney VR46 Racing | 315.7 | 01:43.945 | 0.456 / 0.102 |
| 6 | Fabio Di Giannantonio | Gresini Racing | 305.9 | 01:43.947 | 0.458 / 0.002 |
| 7 | Johann Zarco | Pramac Racing | 314.8 | 01:44.062 | 0.573 / 0.115 |
| 8 | Maverick Viñales | Aprilia Racing | 314.8 | 01:44.117 | 0.628 / 0.055 |
| 9 | Pol Espargaro | GASGAS Tech3 | 313.0 | 01:44.219 | 0.730 / 0.102 |
| 10 | Jack Miller | Red Bull KTM | 312.1 | 01:44.261 | 0.772 / 0.042 |
| 11 | Miguel Oliveira | RNF MotoGP | 313.0 | 01:44.317 | 0.828 / 0.056 |
| 12 | Joan Mir | Repsol Honda | 311.2 | 01:44.428 | 0.939 / 0.111 |
| 13 | Fabio Quartararo | Monster Energy Yamaha | 309.4 | 01:44.520 | 1.031 / 0.092 |
| 14 | Marc Marquez | Repsol Honda | 310.3 | 01:44.574 | 1.085 / 0.054 |
| 15 | Franco Morbidelli | Monster Energy Yamaha | 311.2 | 01:44.657 | 1.168 / 0.083 |
| 16 | Cal Crutchlow* | Yamalube RS4GP Racing | 311.2 | 01:44.709 | 1.220 / 0.052 |
| 17 | Raul Fernandez | RNF MotoGP | 309.4 | 01:44.811 | 1.322 / 0.102 |
| 18 | Takaaki Nakagami | LCR Honda Idemitsu | 309.4 | 01:44.928 | 1.439 / 0.117 |
| 19 | Augusto Fernandez | GASGAS Tech3 | 306.8 | 01:45.231 | 1.742 / 0.303 |
| 20 | Michele Pirro^ | Ducati Lenovo | 308.5 | 01:45.866 | 2.377 / 0.635 |
| 21 | Alex Rins | LCR Honda Castrol | 311.2 | 01:47.236 | 3.747 / 1.370 |
*Wild card entry
^Replaced Enea Bastianini for the Japanese Grand Prix
Note: Mooney VR46 Racing rider Luca Marini and Gresini Racing's Alex Marquez did not take part in the Japanese Grand Prix due to injuries they suffered in India.