MotoGP Practice Results Sepang Malaysia Friday November 10
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Alex Marquez | Gresini Racing | 331.2 | 01:57.823 | |
| 2 | Jorge Martin | Pramac Racing | 333.3 | 01:57.997 | 0.174 / 0.174 |
| 3 | Jack Miller | Red Bull KTM | 334.3 | 01:58.232 | 0.409 / 0.235 |
| 4 | Brad Binder | Red Bull KTM | 334.3 | 01:58.307 | 0.484 / 0.075 |
| 5 | Maverick Viñales | Aprilia Racing | 333.3 | 01:58.312 | 0.489 / 0.005 |
| 6 | Luca Marini | Mooney VR46 Racing | 330.2 | 01:58.334 | 0.511 / 0.022 |
| 7 | Fabio Quartararo | Monster Energy Yamaha | 331.2 | 01:58.399 | 0.576 / 0.065 |
| 8 | Francesco Bagnaia | Ducati Lenovo | 334.3 | 01:58.420 | 0.597 / 0.021 |
| 9 | Marco Bezzecchi | Mooney VR46 Racing | 333.3 | 01:58.450 | 0.627 / 0.030 |
| 10 | Johann Zarco | Pramac Racing | 331.2 | 01:58.487 | 0.664 / 0.037 |
| 11 | Franco Morbidelli | Monster Energy Yamaha | 331.2 | 01:58.571 | 0.748 / 0.084 |
| 12 | Enea Bastianini | Ducati Lenovo | 333.3 | 01:58.605 | 0.782 / 0.034 |
| 13 | Augusto Fernandez | GASGAS Tech3 | 330.2 | 01:58.678 | 0.855 / 0.073 |
| 14 | Fabio Di Giannantonio | Gresini Racing | 327.2 | 01:58.709 | 0.886 / 0.031 |
| 15 | Marc Marquez | Repsol Honda | 332.3 | 01:58.788 | 0.965 / 0.079 |
| 16 | Joan Mir | Repsol Honda | 334.3 | 01:58.902 | 1.079 / 0.114 |
| 17 | Pol Espargaro | GASGAS Tech3 | 332.3 | 01:58.974 | 1.151 / 0.072 |
| 18 | Raul Fernandez | RNF MotoGP | 328.2 | 01:59.024 | 1.201 / 0.050 |
| 19 | Miguel Oliveira | RNF MotoGP | 332.3 | 01:59.150 | 1.327 / 0.126 |
| 20 | Aleix Espargaro | Aprilia Racing | 332.3 | 01:59.726 | 1.903 / 0.576 |
| 21 | Takaaki Nakagami | LCR Honda Idemitsu | 327.2 | 01:59.755 | 1.932 / 0.029 |
| 22 | Alvaro Bautista* | Aruba.it Racing | 326.2 | 02:00.370 | 2.547 / 0.615 |
| 23 | Iker Lecuona^ | LCR Honda Castrol | 328.2 | 02:00.451 | 2.628 / 0.081 |
*Wild card entry
^Replaced Alex Rins for the Malaysian Grand Prix