MotoGP Second Free Practice Results Mandalika Indonesia Saturday September 28
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Franco Morbidelli | Pramac Racing | 313.9 | 01:30.330 | |
| 2 | Aleix Espargaro | Aprilia Racing | 313.0 | 01:30.497 | 0.167 / 0.167 |
| 3 | Marc Marquez | Gresini Racing | 313.0 | 01:30.510 | 0.180 / 0.013 |
| 4 | Francesco Bagnaia | Ducati Lenovo | 315.7 | 01:30.548 | 0.218 / 0.038 |
| 5 | Jorge Martin | Pramac Racing | 315.7 | 01:30.550 | 0.220 / 0.002 |
| 6 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 309.4 | 01:30.567 | 0.237 / 0.017 |
| 7 | Enea Bastianini | Ducati Lenovo | 316.7 | 01:30.582 | 0.252 / 0.015 |
| 8 | Maverick Viñales | Aprilia Racing | 311.2 | 01:30.673 | 0.343 / 0.091 |
| 9 | Fabio Quartararo | Monster Energy Yamaha | 313.0 | 01:30.675 | 0.345 / 0.002 |
| 10 | Pedro Acosta | GASGAS Tech3 | 316.7 | 01:30.720 | 0.390 / 0.045 |
| 11 | Johann Zarco | LCR Honda Castrol | 310.3 | 01:30.735 | 0.405 / 0.015 |
| 12 | Alex Rins | Monster Energy Yamaha | 309.4 | 01:30.803 | 0.473 / 0.068 |
| 13 | Joan Mir | Repsol Honda | 312.1 | 01:30.825 | 0.495 / 0.022 |
| 14 | Augusto Fernandez | GASGAS Tech3 | 312.1 | 01:30.996 | 0.666 / 0.171 |
| 15 | Brad Binder | Red Bull KTM | 317.6 | 01:31.008 | 0.678 / 0.012 |
| 16 | Takaaki Nakagami | LCR Honda Idemitsu | 310.3 | 01:31.010 | 0.680 / 0.002 |
| 17 | Luca Marini | Repsol Honda | 310.3 | 01:31.077 | 0.747 / 0.067 |
| 18 | Alex Marquez | Gresini Racing | 311.2 | 01:31.109 | 0.779 / 0.032 |
| 19 | Marco Bezzecchi | Pertamina Enduro VR46 | 313.9 | 01:31.117 | 0.787 / 0.008 |
| 20 | Jack Miller | Red Bull KTM | 312.1 | 01:31.147 | 0.817 / 0.030 |
| 21 | Raul Fernandez | Trackhouse Racing | 310.3 | 01:31.194 | 0.864 / 0.047 |
Note: Trackhouse Racing rider Miguel Oliveira was declared unfit for the Indonesian Grand Prix after suffering a fractured right wrist in FP1.