MotoGP Second Free Practice Results Motegi Japan Saturday September 27
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Pedro Acosta | Red Bull KTM | 316.7 | 01:44.108 | |
| 2 | Ai Ogura | Trackhouse Racing | 313.0 | 01:44.233 | 0.125 / 0.125 |
| 3 | Marc Marquez | Ducati Lenovo | 316.7 | 01:44.321 | 0.213 / 0.088 |
| 4 | Francesco Bagnaia | Ducati Lenovo | 317.6 | 01:44.338 | 0.230 / 0.017 |
| 5 | Franco Morbidelli | Pertamina Enduro VR46 | 314.8 | 01:44.341 | 0.233 / 0.003 |
| 6 | Luca Marini | Honda HRC Castrol | 315.7 | 01:44.420 | 0.312 / 0.079 |
| 7 | Marco Bezzecchi | Aprilia Racing | 314.8 | 01:44.521 | 0.413 / 0.101 |
| 8 | Takaaki Nakagami* | HRC Team | 313.9 | 01:44.528 | 0.420 / 0.007 |
| 9 | Fabio Quartararo | Monster Energy Yamaha | 312.1 | 01:44.591 | 0.483 / 0.063 |
| 10 | Alex Marquez | Gresini Racing | 312.1 | 01:44.630 | 0.522 / 0.039 |
| 11 | Joan Mir | Honda HRC Castrol | 315.7 | 01:44.634 | 0.526 / 0.004 |
| 12 | Brad Binder | Red Bull KTM | 315.7 | 01:44.644 | 0.536 / 0.010 |
| 13 | Jack Miller | Pramac Racing | 316.7 | 01:44.667 | 0.559 / 0.023 |
| 14 | Fermin Aldeguer | Gresini Racing | 313.9 | 01:44.676 | 0.568 / 0.009 |
| 15 | Jorge Martin | Aprilia Racing | 313.0 | 01:44.873 | 0.765 / 0.197 |
| 16 | Johann Zarco | Castrol Honda LCR | 315.7 | 01:44.882 | 0.774 / 0.009 |
| 17 | Raul Fernandez | Trackhouse Racing | 312.1 | 01:44.892 | 0.784 / 0.010 |
| 18 | Enea Bastianini | KTM Tech3 | 315.7 | 01:44.939 | 0.831 / 0.047 |
| 19 | Miguel Oliveira | Pramac Racing | 315.7 | 01:45.007 | 0.899 / 0.068 |
| 20 | Maverick Viñales | KTM Tech3 | 313.9 | 01:45.079 | 0.971 / 0.072 |
| 21 | Alex Rins | Monster Energy Yamaha | 312.1 | 01:45.143 | 1.035 / 0.064 |
| 22 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 314.8 | 01:45.226 | 1.118 / 0.083 |
| 23 | Somkiat Chantra | Idemitsu Honda LCR | 312.1 | 01:45.946 | 1.838 / 0.720 |
*Wild card entry