Formula 1 First Free Practice Results Mexico City Mexico Friday November 5
| P | Driver | Team | Lap time | Laps |
| 1 | Valtteri Bottas | Mercedes |
01:18.341 | 28 |
| 2 | Lewis Hamilton | Mercedes |
01:18.417 | 24 |
| 3 | Max Verstappen | Red Bull Racing | 01:18.464 | 28 |
| 4 | Sergio Perez | Red Bull Racing | 01:18.610 | 20 |
| 5 | Pierre Gasly | AlphaTauri | 01:18.985 | 23 |
| 6 | Carlos Sainz | Scuderia Ferrari | 01:19.463 | 26 |
| 7 | Fernando Alonso | Alpine | 01:19.656 | 26 |
| 8 | Charles Leclerc | Scuderia Ferrari | 01:19.667 | 20 |
| 9 | Esteban Ocon | Alpine | 01:19.759 | 20 |
| 10 | Sebastian Vettel | Aston Martin | 01:19.858 | 27 |
| 11 | Yuki Tsunoda | AlphaTauri | 01:20.011 | 30 |
| 12 | Kimi Räikkönen | Alfa Romeo | 01:20.026 | 26 |
| 13 | Lance Stroll | Aston Martin | 01:20.030 | 27 |
| 14 | Daniel Ricciardo | McLaren | 01:20.273 | 25 |
| 15 | Lando Norris | McLaren | 01:20.301 | 26 |
| 16 | Antonio Giovinazzi | Alfa Romeo | 01:20.344 | 27 |
| 17 | George Russell | Williams | 01:20.517 | 23 |
| 18 | Nicholas Latifi | Williams | 01:21.580 | 23 |
| 19 | Mick Schumacher | Haas | 01:22.144 | 27 |
| 20 | Nikita Mazepin | Haas | 01:22.819 | 24 |