MotoGP Qualifying Results Misano San Marino Saturday September 9
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Jorge Martin | Pramac Racing | 301.6 | 01:30.390 | |
| 2 | Marco Bezzecchi | Mooney VR46 Racing | 305.9 | 01:30.787 | 0.397 / 0.397 |
| 3 | Francesco Bagnaia | Ducati Lenovo | 300.8 | 01:30.826 | 0.436 / 0.039 |
| 4 | Maverick Viñales | Aprilia Racing | 301.6 | 01:30.916 | 0.526 / 0.090 |
| 5 | Dani Pedrosa* | Red Bull KTM | 304.2 | 01:31.023 | 0.633 / 0.107 |
| 6 | Aleix Espargaro+ | Aprilia Racing | 300.8 | 01:31.082 | 0.692 / 0.059 |
| 7 | Brad Binder | Red Bull KTM | 301.6 | 01:31.103 | 0.713 / 0.021 |
| 8 | Luca Marini | Mooney VR46 Racing | 299.1 | 01:31.210 | 0.820 / 0.107 |
| 9 | Marc Marquez | Repsol Honda | 298.3 | 01:31.223 | 0.833 / 0.013 |
| 10 | Miguel Oliveira+ | RNF MotoGP | 300.0 | 01:31.277 | 0.887 / 0.054 |
| 11 | Alex Marquez | Gresini Racing | 297.5 | 01:31.278 | 0.888 / 0.001 |
| 12 | Raul Fernandez | RNF MotoGP | 298.3 | 01:31.341 | 0.951 / 0.063 |
+Riders advanced from Q1 to Q2
| 13 | Fabio Quartararo | Monster Energy Yamaha | 295.8 | 01:31.467 | 0.195 / 0.038 |
| 14 | Michele Pirro* | Aruba.it Racing | 295.8 | 01:31.533 | 0.261 / 0.066 |
| 15 | Stefan Bradl* | HRC Team | 297.5 | 01:31.560 | 0.288 / 0.027 |
| 16 | Johann Zarco | Pramac Racing | 298.3 | 01:31.667 | 0.395 / 0.107 |
| 17 | Augusto Fernandez | GASGAS Tech3 | 295.8 | 01:31.678 | 0.406 / 0.011 |
| 18 | Jack Miller | Red Bull KTM | 300.0 | 01:31.713 | 0.441 / 0.035 |
| 19 | Franco Morbidelli | Monster Energy Yamaha | 295.0 | 01:31.845 | 0.573 / 0.132 |
| 20 | Takaaki Nakagami | LCR Honda Idemitsu | 297.5 | 01:31.851 | 0.579 / 0.006 |
| 21 | Fabio Di Giannantonio | Gresini Racing | 295.0 | 01:31.914 | 0.642 / 0.063 |
| 22 | Joan Mir | Repsol Honda | 296.7 | 01:31.944 | 0.672 / 0.030 |
| 23 | Pol Espargaro | GASGAS Tech3 | 299.1 | 01:32.140 | 0.868 / 0.196 |
*Wild card entry (3)
Note: LCR Honda Castrol's replacement rider Takumi Takahashi was not allowed to take part in the San Marino Grand Prix following FP2 after having failed to get within the 105% cut-off time in Practice.
Ducati Lenovo rider Enea Bastianini did not take part in the San Marino Grand Prix due to injuries he suffered in Catalonia.