MotoGP Second Free Practice Results Sepang Malaysia Saturday November 11
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Fabio Quartararo | Monster Energy Yamaha | 332.3 | 01:58.960 | |
| 2 | Franco Morbidelli | Monster Energy Yamaha | 332.3 | 01:58.985 | 0.025 / 0.025 |
| 3 | Brad Binder | Red Bull KTM | 333.3 | 01:59.232 | 0.272 / 0.247 |
| 4 | Alex Marquez | Gresini Racing | 333.3 | 01:59.260 | 0.300 / 0.028 |
| 5 | Johann Zarco | Pramac Racing | 330.2 | 01:59.354 | 0.394 / 0.094 |
| 6 | Enea Bastianini | Ducati Lenovo | 332.3 | 01:59.357 | 0.397 / 0.003 |
| 7 | Francesco Bagnaia | Ducati Lenovo | 336.4 | 01:59.394 | 0.434 / 0.037 |
| 8 | Marc Marquez | Repsol Honda | 332.3 | 01:59.398 | 0.438 / 0.004 |
| 9 | Luca Marini | Mooney VR46 Racing | 331.2 | 01:59.501 | 0.541 / 0.103 |
| 10 | Jorge Martin | Pramac Racing | 335.4 | 01:59.517 | 0.557 / 0.016 |
| 11 | Pol Espargaro | GASGAS Tech3 | 332.3 | 01:59.558 | 0.598 / 0.041 |
| 12 | Aleix Espargaro | Aprilia Racing | 330.2 | 01:59.615 | 0.655 / 0.057 |
| 13 | Fabio Di Giannantonio | Gresini Racing | 328.2 | 01:59.675 | 0.715 / 0.060 |
| 14 | Maverick Viñales | Aprilia Racing | 332.3 | 01:59.679 | 0.719 / 0.004 |
| 15 | Jack Miller | Red Bull KTM | 332.3 | 01:59.761 | 0.801 / 0.082 |
| 16 | Raul Fernandez | RNF MotoGP | 328.2 | 01:59.792 | 0.832 / 0.031 |
| 17 | Alvaro Bautista* | Aruba.it Racing | 331.2 | 01:59.835 | 0.875 / 0.043 |
| 18 | Marco Bezzecchi | Mooney VR46 Racing | 333.3 | 01:59.917 | 0.957 / 0.082 |
| 19 | Joan Mir | Repsol Honda | 332.3 | 02:00.044 | 1.084 / 0.127 |
| 20 | Augusto Fernandez | GASGAS Tech3 | 332.3 | 02:00.051 | 1.091 / 0.007 |
| 21 | Takaaki Nakagami | LCR Honda Idemitsu | 326.2 | 02:00.185 | 1.225 / 0.134 |
| 22 | Miguel Oliveira | RNF MotoGP | 330.2 | 02:00.688 | 1.728 / 0.503 |
| 23 | Iker Lecuona^ | LCR Honda Castrol | 329.2 | 02:00.973 | 2.013 / 0.285 |
*Wild card entry
^Replaced Alex Rins for the Malaysian Grand Prix