MotoGP Practice Results Cheste Spain Friday November 24
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Maverick Viñales | Aprilia Racing | 333.7 | 01:29.142 | |
| 2 | Jorge Martin | Pramac Racing | 335.4 | 01:29.289 | 0.147 / 0.147 |
| 3 | Johann Zarco | Pramac Racing | 333.7 | 01:29.296 | 0.154 / 0.007 |
| 4 | Fabio Di Giannantonio | Gresini Racing | 325.8 | 01:29.395 | 0.253 / 0.099 |
| 5 | Marco Bezzecchi | Mooney VR46 Racing | 330.5 | 01:29.396 | 0.254 / 0.001 |
| 6 | Brad Binder | Red Bull KTM | 337.0 | 01:29.402 | 0.260 / 0.006 |
| 7 | Marc Marquez | Repsol Honda | 328.9 | 01:29.459 | 0.317 / 0.057 |
| 8 | Raul Fernandez | RNF MotoGP | 330.5 | 01:29.470 | 0.328 / 0.011 |
| 9 | Jack Miller | Red Bull KTM | 330.5 | 01:29.481 | 0.339 / 0.011 |
| 10 | Aleix Espargaro | Aprilia Racing | 332.1 | 01:29.571 | 0.429 / 0.090 |
| 11 | Enea Bastianini | Ducati Lenovo | 335.4 | 01:29.573 | 0.431 / 0.002 |
| 12 | Alex Marquez | Gresini Racing | 325.8 | 01:29.614 | 0.472 / 0.041 |
| 13 | Fabio Quartararo | Monster Energy Yamaha | 330.5 | 01:29.615 | 0.473 / 0.001 |
| 14 | Franco Morbidelli | Monster Energy Yamaha | 328.9 | 01:29.775 | 0.633 / 0.160 |
| 15 | Francesco Bagnaia | Ducati Lenovo | 333.7 | 01:29.801 | 0.659 / 0.026 |
| 16 | Takaaki Nakagami | LCR Honda Idemitsu | 325.8 | 01:30.002 | 0.860 / 0.201 |
| 17 | Luca Marini | Mooney VR46 Racing | 330.5 | 01:30.343 | 1.201 / 0.341 |
| 18 | Augusto Fernandez | GASGAS Tech3 | 330.5 | 01:30.445 | 1.303 / 0.102 |
| 19 | Alex Rins | LCR Honda Castrol | 330.5 | 01:30.464 | 1.322 / 0.019 |
| 20 | Lorenzo Savadori* | RNF MotoGP | 328.9 | 01:30.795 | 1.653 / 0.331 |
| 21 | Pol Espargaro | GASGAS Tech3 | 332.1 | 01:30.940 | 1.798 / 0.145 |
*Replaced Miguel Oliveira for the Valencia Grand Prix
Note: Repsol Honda rider Joan Mir did not take part in Practice.