MotoGP Second Free Practice Results Portimão Portugal Saturday March 23
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Maverick Viñales | Aprilia Racing | 343.9 | 01:38.720 | |
| 2 | Pedro Acosta | GASGAS Tech3 | 342.8 | 01:39.015 | 0.295 / 0.295 |
| 3 | Aleix Espargaro | Aprilia Racing | 340.6 | 01:39.208 | 0.488 / 0.193 |
| 4 | Marc Marquez | Gresini Racing | 341.7 | 01:39.256 | 0.536 / 0.048 |
| 5 | Raul Fernandez | Trackhouse Racing | 337.5 | 01:39.401 | 0.681 / 0.145 |
| 6 | Jorge Martin | Pramac Racing | 345.0 | 01:39.444 | 0.724 / 0.043 |
| 7 | Francesco Bagnaia | Ducati Lenovo | 346.1 | 01:39.450 | 0.730 / 0.006 |
| 8 | Fabio Quartararo | Monster Energy Yamaha | 341.7 | 01:39.483 | 0.763 / 0.033 |
| 9 | Marco Bezzecchi | Pertamina Enduro VR46 | 340.6 | 01:39.510 | 0.790 / 0.027 |
| 10 | Brad Binder | Red Bull KTM | 346.1 | 01:39.523 | 0.803 / 0.013 |
| 11 | Alex Rins | Monster Energy Yamaha | 341.7 | 01:39.537 | 0.817 / 0.014 |
| 12 | Franco Morbidelli | Pramac Racing | 339.6 | 01:39.543 | 0.823 / 0.006 |
| 13 | Takaaki Nakagami | LCR Honda Idemitsu | 337.5 | 01:39.608 | 0.888 / 0.065 |
| 14 | Alex Marquez | Gresini Racing | 341.7 | 01:39.614 | 0.894 / 0.006 |
| 15 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 340.6 | 01:39.615 | 0.895 / 0.001 |
| 16 | Enea Bastianini | Ducati Lenovo | 341.7 | 01:39.692 | 0.972 / 0.077 |
| 17 | Miguel Oliveira | Trackhouse Racing | 341.7 | 01:39.816 | 1.096 / 0.124 |
| 18 | Johann Zarco | LCR Honda Castrol | 337.5 | 01:39.872 | 1.152 / 0.056 |
| 19 | Jack Miller | Red Bull KTM | 345.0 | 01:39.922 | 1.202 / 0.050 |
| 20 | Augusto Fernandez | GASGAS Tech3 | 341.7 | 01:40.083 | 1.363 / 0.161 |
| 21 | Joan Mir | Repsol Honda | 338.5 | 01:40.244 | 1.524 / 0.161 |
| 22 | Luca Marini | Repsol Honda | 341.7 | 01:40.494 | 1.774 / 0.250 |