Formula 1 First Free Practice Results Mexico City Mexico Friday October 25
| P | Driver | Team | Lap time | Laps |
| 1 | George Russell | Mercedes | 01:17.998 | 24 |
| 2 | Carlos Sainz | Scuderia Ferrari | 01:18.315 | 25 |
| 3 | Yuki Tsunoda | RB | 01:18.699 | 24 |
| 4 | Max Verstappen | Red Bull Racing | 01:18.839 | 14 |
| 5 | Nico Hülkenberg | Haas | 01:18.904 | 18 |
| 6 | Oscar Piastri | McLaren | 01:18.958 | 24 |
| 7 | Esteban Ocon | Alpine | 01:18.996 | 22 |
| 8 | Valtteri Bottas | Kick Sauber | 01:19.048 | 24 |
| 9 | Liam Lawson | RB | 01:19.093 | 26 |
| 10 | Sergio Perez | Red Bull Racing | 01:19.094 | 23 |
| 11 | Franco Colapinto | Williams | 01:19.109 | 21 |
| 12 | Andrea Antonelli* | Mercedes | 01:19.200 | 19 |
| 13 | Patricio O'Ward^ |
McLaren | 01:19.295 | 21 |
| 14 | Kevin Magnussen | Haas | 01:19.335 | 23 |
| 15 | Pierre Gasly | Alpine | 01:19.340 | 20 |
| 16 | Lance Stroll | Aston Martin | 01:19.600 | 18 |
| 17 | Alexander Albon | Williams | 01:19.812 | 7 |
| 18 | Felipe Drugovich° | Aston Martin | 01:19.819 | 17 |
| 19 | Robert Shwartzman+ |
Kick Sauber | 01:19.988 | 18 |
| 20 | Oliver Bearman~ |
Scuderia Ferrari | 01:21.256 | 7 |
*Substitute for Lewis Hamilton
^Substitute for Lando Norris
°Substitute for Fernando Alonso
+Substitute for Zhou Guanyu
~Substitute for Charles Leclerc