MotoGP Practice Results Motegi Japan Friday September 26
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Marco Bezzecchi | Aprilia Racing | 315.7 | 01:43.193 | |
| 2 | Pedro Acosta | Red Bull KTM | 318.5 | 01:43.329 | 0.136 / 0.136 |
| 3 | Marc Marquez | Ducati Lenovo | 315.7 | 01:43.360 | 0.167 / 0.031 |
| 4 | Joan Mir | Honda HRC Castrol | 316.7 | 01:43.361 | 0.168 / 0.001 |
| 5 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 313.9 | 01:43.391 | 0.198 / 0.030 |
| 6 | Luca Marini | Honda HRC Castrol | 314.8 | 01:43.503 | 0.310 / 0.112 |
| 7 | Francesco Bagnaia | Ducati Lenovo | 313.0 | 01:43.539 | 0.346 / 0.036 |
| 8 | Fabio Quartararo | Monster Energy Yamaha | 311.2 | 01:43.594 | 0.401 / 0.055 |
| 9 | Raul Fernandez | Trackhouse Racing | 313.0 | 01:43.666 | 0.473 / 0.072 |
| 10 | Johann Zarco | Castrol Honda LCR | 316.7 | 01:43.734 | 0.541 / 0.068 |
| 11 | Fermin Aldeguer | Gresini Racing | 311.2 | 01:43.742 | 0.549 / 0.008 |
| 12 | Enea Bastianini | KTM Tech3 | 313.9 | 01:43.743 | 0.550 / 0.001 |
| 13 | Jorge Martin | Aprilia Racing | 313.9 | 01:43.784 | 0.591 / 0.041 |
| 14 | Ai Ogura | Trackhouse Racing | 313.9 | 01:43.784 | 0.591 / 0.000 |
| 15 | Alex Marquez | Gresini Racing | 315.7 | 01:43.784 | 0.591 / 0.000 |
| 16 | Franco Morbidelli | Pertamina Enduro VR46 | 313.9 | 01:43.828 | 0.635 / 0.044 |
| 17 | Brad Binder | Red Bull KTM | 315.7 | 01:43.855 | 0.662 / 0.027 |
| 18 | Somkiat Chantra | Idemitsu Honda LCR | 314.8 | 01:43.911 | 0.718 / 0.056 |
| 19 | Alex Rins | Monster Energy Yamaha | 312.1 | 01:44.013 | 0.820 / 0.102 |
| 20 | Jack Miller | Pramac Racing | 314.8 | 01:44.113 | 0.920 / 0.100 |
| 21 | Takaaki Nakagami* | HRC Team | 314.8 | 01:44.202 | 1.009 / 0.089 |
| 22 | Miguel Oliveira | Pramac Racing | 315.7 | 01:44.654 | 1.461 / 0.452 |
| 23 | Maverick Viñales | KTM Tech3 | 314.8 | 01:44.801 | 1.608 / 0.147 |
*Wild card entry