MotoGP Practice Results Sepang Malaysia Friday October 24
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Pedro Acosta | Red Bull KTM | 336.4 | 01:57.559 | |
| 2 | Johann Zarco | Castrol Honda LCR | 333.3 | 01:57.578 | 0.019 / 0.019 |
| 3 | Jack Miller | Pramac Racing | 334.3 | 01:57.840 | 0.281 / 0.262 |
| 4 | Joan Mir | Honda HRC Castrol | 336.4 | 01:57.854 | 0.295 / 0.014 |
| 5 | Fabio Quartararo | Monster Energy Yamaha | 331.2 | 01:57.868 | 0.309 / 0.014 |
| 6 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 333.3 | 01:58.039 | 0.480 / 0.171 |
| 7 | Franco Morbidelli | Pertamina Enduro VR46 | 332.3 | 01:58.041 | 0.482 / 0.002 |
| 8 | Pol Espargaro° | KTM Tech3 | 335.4 | 01:58.055 | 0.496 / 0.014 |
| 9 | Alex Marquez | Gresini Racing | 333.3 | 01:58.057 | 0.498 / 0.002 |
| 10 | Alex Rins | Monster Energy Yamaha | 334.3 | 01:58.117 | 0.558 / 0.060 |
| 11 | Luca Marini | Honda HRC Castrol | 335.4 | 01:58.179 | 0.620 / 0.062 |
| 12 | Francesco Bagnaia | Ducati Lenovo | 332.3 | 01:58.206 | 0.647 / 0.027 |
| 13 | Fermin Aldeguer | Gresini Racing | 329.2 | 01:58.279 | 0.720 / 0.073 |
| 14 | Ai Ogura | Trackhouse Racing | 332.3 | 01:58.300 | 0.741 / 0.021 |
| 15 | Marco Bezzecchi | Aprilia Racing | 335.4 | 01:58.360 | 0.801 / 0.060 |
| 16 | Raul Fernandez | Trackhouse Racing | 330.2 | 01:58.581 | 1.022 / 0.221 |
| 17 | Brad Binder | Red Bull KTM | 334.3 | 01:58.739 | 1.180 / 0.158 |
| 18 | Miguel Oliveira | Pramac Racing | 331.2 | 01:58.776 | 1.217 / 0.037 |
| 19 | Enea Bastianini | KTM Tech3 | 336.4 | 01:58.953 | 1.394 / 0.177 |
| 20 | Somkiat Chantra | Idemitsu Honda LCR | 331.2 | 01:58.964 | 1.405 / 0.011 |
| 21 | Lorenzo Savadori~ | Aprilia Racing | 331.2 | 01:59.252 | 1.693 / 0.288 |
| 22 | Michele Pirro^ | Ducati Lenovo | 331.2 | 01:59.741 | 2.182 / 0.489 |
| 23 | Augusto Fernandez* | Yamaha Factory Racing | 326.2 | 01:59.974 | 2.415 / 0.233 |
*Wild card entry
^Replaced Marc Marquez for the Malaysian Grand Prix
°Replaced Maverick Viñales for the Malaysian Grand Prix
~Replaced Jorge Martin for the Malaysian Grand Prix
Note: Ducati Lenovo rider Marc Marquez (right shoulder injury recovery), Red Bull KTM Tech3's Maverick Viñales (left shoulder injury recovery) and Aprilia Racing rider Jorge Martin (right shoulder injury recovery) were ruled out of the Malaysian Grand Prix.