Formula 1 First Free Practice Results Mexico City Mexico Friday October 24
| P | Driver | Team | Lap time | Laps |
| 1 | Charles Leclerc | Scuderia Ferrari | 01:18.380 | 29 |
| 2 | Andrea Antonelli | Mercedes | 01:18.487 | 35 |
| 3 | Nico Hülkenberg | Kick Sauber | 01:18.760 | 27 |
| 4 | Oscar Piastri | McLaren | 01:18.784 | 31 |
| 5 | Gabriel Bortoleto | Kick Sauber | 01:18.916 | 28 |
| 6 | Arvid Lindblad* | Red Bull Racing | 01:18.997 | 26 |
| 7 | Esteban Ocon | Haas | 01:19.038 | 29 |
| 8 | Yuki Tsunoda | Red Bull Racing | 01:19.090 | 29 |
| 9 | Franco Colapinto | Alpine | 01:19.331 | 28 |
| 10 | Alexander Albon | Williams | 01:19.384 | 33 |
| 11 | Isack Hadjar | Racing Bulls | 01:19.409 | 32 |
| 12 | Fernando Alonso | Aston Martin | 01:19.472 | 26 |
| 13 | Patricio O'Ward^ | McLaren | 01:19.680 | 30 |
| 14 | Frederik Vesti° | Mercedes | 01:19.689 | 32 |
| 15 | Paul Aron+ | Alpine | 01:19.862 | 29 |
| 16 | Ryo Hirakawa~ | Haas | 01:20.073 | 27 |
| 17 | Ayumu Iwasa** | Racing Bulls | 01:20.153 | 29 |
| 18 | Luke Browning^^ | Williams | 01:20.310 | 31 |
| 19 | Jak Crawford°° | Aston Martin | 01:20.371 | 29 |
| 20 | Antonio Fuoco++ | Scuderia Ferrari | 01:20.854 | 29 |
*Substitute for Max Verstappen
^Substitute for Lando Norris
°Substitute for George Russell
+Substitute for Pierre Gasly
~Substitute for Oliver Bearman
**Substitute for Liam Lawson
^^Substitute for Carlos Sainz
°°Substitute for Lance Stroll
++Substitute for Lewis Hamilton