Formula 1 Second Free Practice Results Mexico City Mexico Friday October 24
| P | Driver | Team | Lap time | Laps |
| 1 | Max Verstappen | Red Bull Racing | 01:17.392 | 34 |
| 2 | Charles Leclerc | Scuderia Ferrari | 01:17.545 | 32 |
| 3 | Andrea Antonelli | Mercedes | 01:17.566 | 27 |
| 4 | Lando Norris | McLaren | 01:17.643 | 31 |
| 5 | Lewis Hamilton | Scuderia Ferrari | 01:17.692 | 30 |
| 6 | George Russell | Mercedes | 01:17.829 | 33 |
| 7 | Yuki Tsunoda | Red Bull Racing | 01:17.883 | 31 |
| 8 | Fernando Alonso | Aston Martin | 01:17.938 | 29 |
| 9 | Carlos Sainz | Williams | 01:17.939 | 34 |
| 10 | Lance Stroll | Aston Martin | 01:17.954 | 30 |
| 11 | Liam Lawson | Racing Bulls | 01:18.218 | 32 |
| 12 | Oscar Piastri | McLaren | 01:18.232 | 31 |
| 13 | Esteban Ocon | Haas | 01:18.266 | 31 |
| 14 | Isack Hadjar | Racing Bulls | 01:18.281 | 30 |
| 15 | Gabriel Bortoleto | Kick Sauber | 01:18.323 | 30 |
| 16 | Nico Hülkenberg | Kick Sauber | 01:18.348 | 29 |
| 17 | Oliver Bearman | Haas | 01:18.442 | 34 |
| 18 | Franco Colapinto | Alpine | 01:18.721 | 31 |
| 19 | Alexander Albon | Williams | 01:18.855 | 31 |
| 20 | Pierre Gasly | Alpine | 01:19.194 | 30 |