MotoGP Practice Results Portimão Portugal Friday November 7
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Alex Marquez | Gresini Racing | 343.9 | 01:37.974 | |
| 2 | Francesco Bagnaia | Ducati Lenovo | 345.0 | 01:38.004 | 0.030 / 0.030 |
| 3 | Pedro Acosta | Red Bull KTM | 347.2 | 01:38.062 | 0.088 / 0.058 |
| 4 | Marco Bezzecchi | Aprilia Racing | 347.2 | 01:38.133 | 0.159 / 0.071 |
| 5 | Joan Mir | Honda HRC Castrol | 346.1 | 01:38.183 | 0.209 / 0.050 |
| 6 | Johann Zarco | Castrol Honda LCR | 345.0 | 01:38.232 | 0.258 / 0.049 |
| 7 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 341.7 | 01:38.302 | 0.328 / 0.070 |
| 8 | Fermin Aldeguer | Gresini Racing | 338.5 | 01:38.382 | 0.408 / 0.080 |
| 9 | Pol Espargaro^ | KTM Tech3 | 346.1 | 01:38.424 | 0.450 / 0.042 |
| 10 | Ai Ogura | Trackhouse Racing | 343.9 | 01:38.443 | 0.469 / 0.019 |
| 11 | Luca Marini | Honda HRC Castrol | 345.0 | 01:38.551 | 0.577 / 0.108 |
| 12 | Franco Morbidelli | Pertamina Enduro VR46 | 342.8 | 01:38.597 | 0.623 / 0.046 |
| 13 | Fabio Quartararo | Monster Energy Yamaha | 339.6 | 01:38.598 | 0.624 / 0.001 |
| 14 | Brad Binder | Red Bull KTM | 346.1 | 01:38.653 | 0.679 / 0.055 |
| 15 | Raul Fernandez | Trackhouse Racing | 342.8 | 01:38.762 | 0.788 / 0.109 |
| 16 | Jack Miller | Pramac Racing | 345.0 | 01:38.874 | 0.900 / 0.112 |
| 17 | Nicolò Bulega* | Ducati Lenovo | 341.7 | 01:38.986 | 1.012 / 0.112 |
| 18 | Alex Rins | Monster Energy Yamaha | 341.7 | 01:39.070 | 1.096 / 0.084 |
| 19 | Enea Bastianini | KTM Tech3 | 343.9 | 01:39.130 | 1.156 / 0.060 |
| 20 | Somkiat Chantra | Idemitsu Honda LCR | 341.7 | 01:39.798 | 1.824 / 0.668 |
| 21 | Lorenzo Savadori° | Aprilia Racing | 341.7 | 01:39.858 | 1.884 / 0.060 |
| 22 | Miguel Oliveira | Pramac Racing | 340.6 | 01:39.881 | 1.907 / 0.023 |
*Replaced Marc Marquez for the Portuguese Grand Prix
^Replaced Maverick Viñales for the Portuguese Grand Prix
°Replaced Jorge Martin for the Portuguese Grand Prix
Note: Ducati Lenovo rider Marc Marquez (right shoulder injury recovery), Red Bull KTM Tech3's Maverick Viñales (left shoulder injury recovery) and Aprilia Racing rider Jorge Martin (right shoulder injury recovery) were ruled out of the Portuguese Grand Prix.