MotoGP Qualifying Results Misano Italy Saturday September 21
| P | Rider | Team | Km/h | Lap time | Gap 1st/Prev. |
|---|---|---|---|---|---|
| 1 | Francesco Bagnaia | Ducati Lenovo | 301.6 | 01:30.031 | |
| 2 | Jorge Martin | Pramac Racing | 304.2 | 01:30.245 | 0.214 / 0.214 |
| 3 | Enea Bastianini | Ducati Lenovo | 299.1 | 01:30.564 | 0.533 / 0.319 |
| 4 | Brad Binder+ | Red Bull KTM | 302.5 | 01:30.636 | 0.605 / 0.072 |
| 5 | Pedro Acosta | GASGAS Tech3 | 303.3 | 01:30.731 | 0.700 / 0.095 |
| 6 | Marco Bezzecchi | Pertamina Enduro VR46 | 305.0 | 01:30.837 | 0.806 / 0.106 |
| 7 | Marc Marquez | Gresini Racing | 297.5 | 01:30.880 | 0.849 / 0.043 |
| 8 | Maverick Viñales | Aprilia Racing | 298.3 | 01:30.909 | 0.878 / 0.029 |
| 9 | Fabio Quartararo | Monster Energy Yamaha | 295.0 | 01:30.921 | 0.890 / 0.012 |
| 10 | Franco Morbidelli | Pramac Racing | 301.6 | 01:30.932 | 0.901 / 0.011 |
| 11 | Aleix Espargaro | Aprilia Racing | 300.8 | 01:31.037 | 1.006 / 0.105 |
| 12 | Miguel Oliveira+ | Trackhouse Racing | 304.2 | 01:31.114 | 1.083 / 0.077 |
+Riders advanced from Q1 to Q2
| 13 | Fabio Di Giannantonio | Pertamina Enduro VR46 | 298.3 | 01:31.285 | 0.215 / 0.139 |
| 14 | Raul Fernandez | Trackhouse Racing | 298.3 | 01:31.402 | 0.332 / 0.117 |
| 15 | Luca Marini | Repsol Honda | 297.5 | 01:31.428 | 0.358 / 0.026 |
| 16 | Joan Mir | Repsol Honda | 301.6 | 01:31.450 | 0.380 / 0.022 |
| 17 | Johann Zarco | LCR Honda Castrol | 300.0 | 01:31.501 | 0.431 / 0.051 |
| 18 | Augusto Fernandez | GASGAS Tech3 | 297.5 | 01:31.554 | 0.484 / 0.053 |
| 19 | Jack Miller | Red Bull KTM | 300.0 | 01:31.695 | 0.625 / 0.141 |
| 20 | Takaaki Nakagami | LCR Honda Idemitsu | 295.8 | 01:32.061 | 0.991 / 0.366 |
| 21 | Alex Marquez | Gresini Racing | 299.1 | 01:32.332 | 1.262 / 0.271 |
Note: Monster Energy Yamaha rider Alex Rins withdrew from the Emilia Romagna Grand Prix following FP2 due to illness.